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MicroRNA miRNA is a class of highly
2021-08-05
MicroRNA (miRNA) is a class of highly conserved, non-coding small molecules containing 19–25 nucleotides. miRNAs are involved in the regulation of genes associated with cancer development and progression and therefore can act as oncogenes, by contributing to tumor formation,17, 18 or as tumor suppre
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DPNI-caged-GABA Several reports have exploited the
2021-08-05
Several reports , , , , have exploited the application of HRM for detecting differentially methylated DNA. Even though DNA methylation analysis by HRM cannot determine the methylation status of individual CpGs, it does provide a robust and inexpensive method to differentiate DNA based on the overal
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br As mentioned above defects
2021-08-05
As mentioned above, defects in the DNA ligase IIIα-interacting protein TDP1 have been identified as the cause of the hereditary neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy 1 (El-Khamisy et al., 2005). In addition, defects in two other DNA repair proteins, aprataxin and
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br Discussion EFTs are sarcomas with almost
2021-08-04
Discussion EFTs are sarcomas with almost undifferentiated histologic features, consequently their differentiation from other small, blue, round cell tumors may be difficult. Substantial intracellular g to mol calculator on PAS stain is a useful diagnostic feature. The addition of CD99 and FLI1 im
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Here two labs that helped characterize these
2021-08-04
Here, two labs that helped characterize these two pathways have worked together to further test whether these apparently parallel pathways from β-AR to CaMKII-RyR might be related in series. Much of the work leading to the Epac pathway involved measurement of Ca sparks as an index of SR Ca leak, oft
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BMS-509744 In looking at exist http www apexbt
2021-08-04
In looking at existing FGE substrates from other organisms, there are no reported effects on conversion efficiency of the general XCXPXRX pattern with respect to placement within or at the N′ or C′ terminus of polypeptides, and it has been suggested that the aldehyde formation is independent of the
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PRRSV is a single stranded positive sense enveloped RNA viru
2021-08-04
PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV VU 0155069 is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The 3′ end of the genome e
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Our data furthermore suggest that Ch h induced oxysterols co
2021-08-04
Our data furthermore suggest that Ch25h-induced oxysterols could play an important role in modulating the immune cell migration. Mechanistically, we observed impaired trafficking of CD44+CD4+ T cells in mice deficient for Ch25h. CD44+CD4+ T cells lacking EBI2, the receptor of 7α-25OHC, were delayed
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br Cytokine profile in MPN Results from experimental
2021-08-03
Cytokine profile in MPN: Results from experimental investigation Cytokines are small molecules constituted by proteins or glycoproteins, which regulate the immune cell function and the immune system. They are secreted mainly by immune ABH but also by other cells such as epithelial cells in respon
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Experiments on the rat model
2021-08-03
Experiments on the rat model of E. coli pyelonephritis, performed to investigate the relationship between the acute inflammatory processes and the permanent kidney damage (Brooks et al., 1974), have demonstrated a positive correlation between the degree of free radical-mediated renal injury and the
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br Results br Discussion Cell
2021-08-03
Results Discussion Cell responds to fluctuating environmental factors by activating a set of compensatory mechanisms including changes in the lipid profile. Compensatory reactions occurring in membranes in response to phosphate deprivation include replacement of phospholipids by phosphorus-fre
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Concerning firmness postharvest calcium dips for whole fruit
2021-08-03
Concerning firmness, postharvest calcium dips for whole fruit have been demonstrated to preserve firmness, cell wall structure (Glenn and Poovaiah, 1990), nutritional quality (Goldberg, 1984) and fruit flavour (Ortiz et al., 2009). Similarly, combinations of calcium treatment (0.5–4%) with packaging
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A recent analysis of urine samples collected from men
2021-08-03
A recent analysis of 2721 urine samples collected from 245 men and 408 women across the US general population between 2005 and 2010 showed that MP, PP and BuP were measurable in 99.9%, 98.3% and 73.6% of samples from women and 99.3%, 90.2% and 35.9% of samples from men, respectively (Smith et al., 2
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br Introduction The innate immune system
2021-08-02
Introduction The innate immune system stands the first line of the defense that protects the host from viral intrusion, depending on pattern recognition receptors (PRRs) and the corresponding pathways [[1], [2], [3], [4]]. The pathogen-associated molecular patterns (PAMPs) of the invading viruses
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Support for Cloninger s personality
2021-08-02
Support for Cloninger's personality theory comes also from molecular genetic studies. Given the high heritability of personality it is plausible that gene variants explain variance in RD. In DL-Dithiothreitol synthesis to endocrine studies, which relate hormone levels mostly in the periphery (blood
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