• Estimates of life expectancy are of

  2019-04-20

  

  Estimates of life expectancy are of obvious importance to people with HIV-1, and are essential to monitor and predict the progress of the HIV/AIDS epidemic and to plan health services. The Rwandan study reported by Sabin Nsanzimana and colleagues in is the first from sub-Saharan Africa to focus on t

• With the publication of this month

  2019-04-20

  

  With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy int

• mmae Real time quantitative polymerase chain reaction

  2019-04-20

  

  Real-time quantitative polymerase chain reaction (RQ-PCR) was performed to quantify BCR/ABL1 transcript as described previously [1]. The quantitative results were expressed as percent ratios relative to an ABL1 internal control using the following formula (p210 BCR–ABL/ABL1×100×CF) [2]. The level of

• TAPI-1 Prior case reports have described hematological remis

  2019-04-20

  

  Prior case reports have described hematological remission in patients with myelofibrosis during treatment with bisphosphonates, but a phase II study investigating the effects of zoledronic TAPI-1 on patients with myelofibrosis showed responses in only 1 of 16 patients[13]. In conclusion, we report

• In an earlier study we used a

  2019-04-20

  

  In an earlier study, we used a questionnaire to assess musculoskeletal pain in patients with CML who had achieved DMR (MR4.0) and discontinued TKI treatment, including IM, nilotinib, and dasatinib [5]. Nine out of the 27 patients surveyed developed musculoskeletal pain after discontinuing TKIs. In

• Rapalink-1 br Authorship br Conflict of interest br Acknowle

  2019-04-19

  

  Authorship Conflict of interest Acknowledgments The Leukemia & Lymphoma Society supported CRC with a Scholar in Clinical Research award (2400-13). This work was supported by the Gatorade Trust from the University of Florida Department of Medicine. Introduction Klinefelter syndrome (KS),

• olmesartan medoxomil br Hematopoietic cell transplantation H

  2019-04-19

  

  Hematopoietic cell transplantation HCT is generally recommended for AML patients with intermediate or high risk cytogenetics, when the aim of treatment is curative. However, elderly patients are seldom offered a transplant mainly due to concerns regarding toxicity, despite the fact that the main

• br In the cluster randomised

  2019-04-19

  

  In the cluster randomised controlled trial by Marcel Yotebieng and colleagues (August, 2015) the addition of Step 10 of the UNICEF Baby Friendly Hospital Initiative (BFHI)—that is, the provision of additional support for breastfeeding—did not enhance the effects of steps 1–9, and may even have les

• br Materials and methods br Results br Discussion

  2019-04-19

  

  Materials and methods Results Discussion The data in the present study showed that ABZ induces SIRT3 downregulation and SIRT3 overexpression attenuates the microtubule-destabilizing effect of ABZ in U937 cells. In agreement, previous studies have revealed that SIRT3 overexpression inhibits

• Introduction Atrial fibrillation AF is a highly

  2019-04-19

  

  Introduction Atrial fibrillation (AF) is a highly prevalent atrial arrhythmia that affects approximately 10% of individuals older than 75 years of age and tends to increase in prevalence with advancing age [1–3]. Although AF itself is not life threatening, it is a risk factor for stroke, and the AF

• prostaglandin receptor br Method br Results br

  2019-04-19

  

  Method Results Discussion The present evaluation of ΔFCL in chronic AF patients over a long-term observation prostaglandin receptor revealed a few interesting findings. First, at the end of the 6-year observation period, the mean FCL had prolonged from 154±20ms to 187±37ms in patients with

• meclofenamate br Acknowledgments The authors would like

  2019-04-19

  

  Acknowledgments The authors would like to thank Sarah Mack for technical assistance with the histology and IHC. We would also like to acknowledge Dr. Gregory Dieudonne in the Department of Musculoskeletal Radiology, University of Rochester Medical Center for advice and assistance in manuscript wr

• br Materials and methods br Results

  2019-04-19

  

  Materials and methods Results Discussion Osteosarcoma derives from primitive bone-forming mesenchymal cells and is the most common type of primary bone malignancy [20]. Over the past few decades, the introduction of combinatorial chemotherapy has improved the 5-year overall survival rate of

• In this study all tumors were

  2019-04-19

  

  In this study, all tumors were Campanacci stage 3, which is a significantly higher proportion than in our database [9]. Such a high stage usually suggests that a tumor is highly aggressive and may be a high-risk factor for lung metastasis. Previous reports have also suggested that the stage of a GCT

• br Conflict of interest br Introduction

  2019-04-19

  

  Conflict of interest Introduction Catheter ablation is an effective approach for the management of patients with atrial fibrillation (AF) [1–7]. Pulmonary vein isolation (PVI) is one of the most common strategies of AF ablation, but the outcome of PVI alone for patients with persistent AF is p

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