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br Experiments br Numerical simulations br Discussion
2021-08-05
Experiments Numerical simulations Discussion Conclusions By large-caliber PELE with various d/D against RHA plate at low velocity of 415 m s−1, impact experiments against 30 mm RHA target were carried out. Numerical simulations were also conducted to monitor progress of PELE expansion an
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87 59 EP is the major receptor to mediate PGE induced
2021-08-05
EP4 is the major receptor to mediate PGE2-induced inflammatory pain. EP4 is upregulated by 87 59 in DRG neurons [16]. Intrathecal injection of the EP4 agonist produced pain responses [25]. Either systemic or local injection of EP4 antagonists relieves inflammatory pain [3], [16], [26]. However, the
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Exo1 Quantifying diffusion is greatly complicated by the ubi
2021-08-05
Quantifying Exo1 is greatly complicated by the ubiquitous unevenness of soil surfaces and related water films, which introduce a large uncertainty into size (area) and quality of contact between the soil surface and the membrane, the problem being particularly substantial in well aggregated and coa
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Interestingly our analyses of human
2021-08-05
Interestingly, our analyses of human PBMCs using a monoclonal antibody against EBI2 showed that the expression pattern of human EBI2 is largely overlapping with that in mice. Especially Th17 N-Nonyldeoxynojirimycin showed homogeneous high expression of EBI2 compared with Th1 cells, which contained a
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MuRF and MuRF in http www apexbt com
2021-08-05
MuRF1 and MuRF3 in cooperation with the E2 ubiquitin-conjugating enzymes UbcH5a, -b, and -c were found to mediate degradation of myosin heavy chain β/slow (MHC β/slow) and MHC IIa via UPS, both, in vitro and in vivo [60]. Mice lacking both MuRF1 and MuRF3 developed skeletal muscle myopathy and hyper
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MicroRNA miRNA is a class of highly
2021-08-05
MicroRNA (miRNA) is a class of highly conserved, non-coding small molecules containing 19–25 nucleotides. miRNAs are involved in the regulation of genes associated with cancer development and progression and therefore can act as oncogenes, by contributing to tumor formation,17, 18 or as tumor suppre
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DPNI-caged-GABA Several reports have exploited the
2021-08-05
Several reports , , , , have exploited the application of HRM for detecting differentially methylated DNA. Even though DNA methylation analysis by HRM cannot determine the methylation status of individual CpGs, it does provide a robust and inexpensive method to differentiate DNA based on the overal
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br As mentioned above defects
2021-08-05
As mentioned above, defects in the DNA ligase IIIα-interacting protein TDP1 have been identified as the cause of the hereditary neurodegenerative disease, spinocerebellar ataxia with axonal neuropathy 1 (El-Khamisy et al., 2005). In addition, defects in two other DNA repair proteins, aprataxin and
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br Discussion EFTs are sarcomas with almost
2021-08-04
Discussion EFTs are sarcomas with almost undifferentiated histologic features, consequently their differentiation from other small, blue, round cell tumors may be difficult. Substantial intracellular g to mol calculator on PAS stain is a useful diagnostic feature. The addition of CD99 and FLI1 im
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Here two labs that helped characterize these
2021-08-04
Here, two labs that helped characterize these two pathways have worked together to further test whether these apparently parallel pathways from β-AR to CaMKII-RyR might be related in series. Much of the work leading to the Epac pathway involved measurement of Ca sparks as an index of SR Ca leak, oft
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BMS-509744 In looking at exist http www apexbt
2021-08-04
In looking at existing FGE substrates from other organisms, there are no reported effects on conversion efficiency of the general XCXPXRX pattern with respect to placement within or at the N′ or C′ terminus of polypeptides, and it has been suggested that the aldehyde formation is independent of the
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PRRSV is a single stranded positive sense enveloped RNA viru
2021-08-04
PRRSV is a single-stranded, positive-sense enveloped RNA virus in the family Arteriviridae of the order Nidovirales (Meng et al., 1994, 1996). The PRRSV VU 0155069 is approximately 15 kb in length and contains eleven known open reading frames (ORFs) (Snijder et al., 2013). The 3′ end of the genome e
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Our data furthermore suggest that Ch h induced oxysterols co
2021-08-04
Our data furthermore suggest that Ch25h-induced oxysterols could play an important role in modulating the immune cell migration. Mechanistically, we observed impaired trafficking of CD44+CD4+ T cells in mice deficient for Ch25h. CD44+CD4+ T cells lacking EBI2, the receptor of 7α-25OHC, were delayed
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br Cytokine profile in MPN Results from experimental
2021-08-03
Cytokine profile in MPN: Results from experimental investigation Cytokines are small molecules constituted by proteins or glycoproteins, which regulate the immune cell function and the immune system. They are secreted mainly by immune ABH but also by other cells such as epithelial cells in respon
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Experiments on the rat model
2021-08-03
Experiments on the rat model of E. coli pyelonephritis, performed to investigate the relationship between the acute inflammatory processes and the permanent kidney damage (Brooks et al., 1974), have demonstrated a positive correlation between the degree of free radical-mediated renal injury and the
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