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br Author contributions br Conflicts
2018-11-05
Author contributions Conflicts of Interest Introduction With 15 million units transfused per year, red blood cell (RBC) transfusion is the most common procedure performed in United States hospitals (Pfuntner et al., 2013). Exposure to numerous foreign non-ABO RBC antigens during transfusion
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Polyubiquitylation leading to proteolytic degradation
2018-11-05
Polyubiquitylation leading to proteolytic degradation by the 26S proteasome is involved in all aspects of cell physiology. The highly coordinated process ensures the selective and timely turnover of proteins, thereby controlling cellular activity and maintaining cell and tissue homeostasis (Glickman
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Early trials on the mg
2018-11-05
Early trials on the 0.75mg/kg dose reported variable reductions in gametocyte carriage (El-Sayed et al., 2007; Shekalaghe et al., 2011; von Seidlein et al., 2003) and a dose-ranging trial in clinically ill patients showed efficacy at doses as low as 0.40mg/kg (Eziefula et al., 2014a); however, non-i
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The following are the supplementary data related to
2018-11-05
The following are the supplementary data related to this article. Funding Sources T.I. is supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) no. 26461257, and Yokohama Foundation for Advancement of Medical Science.
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The gene therapy group had a trend towards
2018-11-05
The gene therapy group had a trend towards fewer ranibizumab retreatments than the control group, and in a post hoc analysis 11 (53%) gene therapy patients received ≤2 ranibizumab retreatments, with the majority having improved vision. A cohort of the gene therapy group received >2 ranibizumab retre
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It has previously been hypothesised that iron supplementatio
2018-11-05
It has previously been hypothesised that iron supplementation increases malaria susceptibility by increasing the availability of \'s preference for young RBCs (). observed significant shifts in RBC populations following iron supplementation, finding younger RBCs are most prevalent at Day 49 post ir
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This year is a year of extraordinary changes for
2018-11-05
This year 2016 is a year of extraordinary changes for this journal. The – (formerly – ) has been repositioned to be a journal with international projection especially interested in addressing current issues in the frontier of knowledge in the marketing field. In this new cycle, the is fully com
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br Disclosure statement br Acknowledgements
2018-11-05
Disclosure statement Acknowledgements The authors thank Australian Wool Innovation Ltd (AWI) for financial support for the project that yielded material discussed in this article. Introduction Scientific study of human sleep has been initiated by the discovery that sleep progresses through
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br Sleep study A Type III home sleep study
2018-11-05
Sleep study A Type III home sleep study was performed using Embletta Portable Diagnostic System (Stowood Scientific Instruments, Oxford UK) and Somnologica software (Embla, Broomfield, USA) for analysis, due to the comparability in diagnosing adult patients with a high probability of moderate to
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br Materials and methods br Results br Discussion
2018-11-05
Materials and methods Results Discussion The results support our hypothesis that the pro/anti-inflammatory complement components can predict PSG sleep measures. The associations between objective sleep measures and inflammatory complement components are similar to those between objective sl
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PLMs index AH average of snoring h and Total sleep
2018-11-05
PLMs index, AHÍ, average of snoring/h, and Total sleep time (TST) showed significant differences as expected by the inclusion criteria of groups (see Table 3). Cardio-respiratory variables showed a decrease percentage of oxygen saturation in the group of PLMs/severe OSAHS and OSAHS only, in relation
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The existence of sex differences in the response to caffeine
2018-11-05
The existence of sex differences in the response to caffeine in young subjects have been studied in humans [8,20] and rodents [21–23], with different conclusions. Soellner et al. [24] reported improved object-discrimination in female rats, following caffeine ingestion. Elkins et al. [20], looking at
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LY 2157299 Disclosure br Acknowledgements Work by PV and
2018-11-03
Disclosure Acknowledgements Work by PV and ML is supported by the Intramural Research Program, NIDDK, NIH (DK053212-11). Since the time when, the endocrine pathology society meeting, held at the 2015 USCAP in Boston, suggested the change in the terminology for encapsulated/non-invasive (NI-FV
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Even if the DP of
2018-11-03
Even if the DP of the method calculated from this study is >0.99 (DP=0.995, as compared to 0.992 in our previous study (Gits-Muselli et al., 2015)), the distance between P. jirovecii genotypes remains low using our MLP typing method, resulting in a limited number of genetic groups. This low genetic
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br Protein sub cellular localization Information about
2018-11-03
Protein sub-cellular localization Information about the sub-cellular localization of the differentially abundant proteins was gained by using the YLoc prediction system (www.multiloc.org/YLoc) based on the YLoc+ model for fungal proteins [10]. The prediction was carried out according to the biolo
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