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One of the interesting aspects
2018-10-23
One of the interesting aspects of the findings in this study is the dissociation between the large phase advances/delays observed in the biochemical rhythms and the much more moderate changes in the sleep/wake cycle. We believe that this discrepancy mainly derives from the environmental/behavioral c
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Additionally we believe it would have
2018-10-23
Additionally, we believe it would have been valuable to investigate the presence of disturbed conditioned pain modulation (CPM) or inefficient descending pain inhibition in the chronic WAD group compared to controls. Subsequently, the efficacy of CPM could have been correlated with the rCBF of regio
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XAV939 Based on the less than expected changes in sCD and
2018-10-23
Based on the less than expected changes in sCD14 and Lp-PLA2 in both arms, in spite of virologic control, we wanted to investigate changes in lipid levels as a potential contributor to immune activation in this study. At weeks 24 and 48, there were small, statistically significant differences in inc
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antioxidants Ependymal cell derived astrocytes are located a
2018-10-23
Ependymal cell-derived astrocytes are located at the core of the lesion site, while resident astrocytes proliferate and are recruited at the border of the lesion site after spinal cord injury (Barnabe-Heider and Frisen, 2008; Burda and Sofroniew, 2014). It was demonstrated that ageing changes the as
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We first confirmed PDLIM overexpression
2018-10-23
We first confirmed PDLIM2 overexpression in primary meningioma and schwannoma samples and showed that it is not expressed in HMC or normal meningeal tissue and minimally expressed in the Schwann cell examined. PDLIM2 was significantly knocked down in three primary meningioma and three primary schwan
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Any intravitreally injected substance must prove efficacy an
2018-10-23
Any intravitreally injected substance must prove efficacy and safety. While our study was not designed as a preclinical safety study, we did not find any obvious structural changes after Sema3f treatment in either of the two in vivo models, which is not surprising given that Sema3f is physiologicall
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Importantly no significant difference in cytoplasmic PD L ex
2018-10-23
Importantly, no significant difference in cytoplasmic PD-L1 ion channel between benign and NIFTP subgroups suggests that NIFTPs are more close to benign nodules, supporting the new paradigm for classification of NIFTP as non-malignant neoplasms (Maletta et al., 2016; Nikiforov et al., 2016; Patel,
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To investigate the translatability of CR s
2018-10-23
To investigate the translatability of CR\'s beneficial effects from rodents to primates, three independent rhesus monkey studies were initiated in the late 1980\'s. Two of these studies are ongoing: one at the National Institute on Aging (NIA) and the other at the Wisconsin National Primate Research
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br Data analysis The data acquired by
2018-10-23
Data analysis The data acquired by Analyst QS 2.0 software was further processed for peak list generation, protein identification, and peptide quantification using ProteinPilot™ software 3.0 (revision number 114732; Applied Biosystems, Foster City, CA). The Paragon algorithm in the ProteinPilot™
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Specifications table br Value of data br Experimental design
2018-10-23
Specifications table Value of data 1. Experimental design, materials and methods 2. Direct link to deposited data Deposited data can be found here: http://www.ncbi.nlm.nih.gov.eleen.top/GBRH01000000. 3. Nucleotide sequence accession number The assembled and annotated A. donax USA KB-R7
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erk pathway HIV co receptor tropism was assessed from the fi
2018-10-23
HIV-1 co-receptor erk pathway was assessed from the filtered V3 MPS data using the g2p [454] tool and classified as X4 when there were more than 2% of the sequences with g2p false positivity rate (FPR) cutoffs of 3.75%, 2.5% and 1%. More detailed analysis was performed at FPR set at 2.5% to increas
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br Experimental design materials and methods br Acknowledgme
2018-10-23
Experimental design, materials and methods Acknowledgments This work was supported by Grants #16791 (EA, AK, CC, SS) and #16442 (JJL, BC), thesis fellowship (EA) and Post-doctoral fellowship (JJL) from the Association Française Contre les Myopathies – Telethon. We thank the imaging platform of
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br Experiment br Results and discussion br Conclusions br Ac
2018-10-22
Experiment Results and discussion Conclusions Acknowledgments The authors thankfully acknowledge the financial support from the Defence Research and Development Organization, Ministry of Defence, Govt. of India, New Delhi in order to carry out the present study. They are grateful to Dire
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The Hybrid cased charge split along the
2018-10-22
The Hybrid cased charge split along the axial grooves producing large heavy fragments (Fig. 15). The Buxton liner in the high mode generated regular shallow cuts into the case, but the cuts did not appear deep enough to promote regular fracture across the strips defined by the grooves. Occasionally
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br Para cerrar escapar del g nero
2018-10-22
Para cerrar: ¿escapar del género? Preguntarse si el género es un significante vacío permite considerar la importancia de pensar después el espacio semántico construido por dicho término como el lugar potencial de un desacuerdo —dado que los múltiples significados posibles están en debate constant
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