• (±)-Nutlin-3 The Zika virus epidemic is

  2019-05-09

  

  The Zika virus epidemic is spreading: 63 countries are now reporting transmission, over 1500 cases of related microcephaly or CNS malformations have been confirmed this year, and knowledge on the disease is advancing slowly. Adding to the tension around Zika, at the epicentre of the outbreak, Brazil

• We did a qualitative analysis to

  2019-05-09

  

  We did a qualitative analysis to estimate the potential risk of Zika atp gamma s introduction into the country. We used the circlize statistical package for R software to visualise incoming traffic (logarithm of relative passenger volume) to Pakistani airports from countries characterised as Zika-v

• br Intrauterine insemination IUI is one of the more widely

  2019-05-09

  

  Intrauterine insemination (IUI) is one of the more widely used fertility treatments, and often suggested as the first choice for infertile couples with cervical infertility, mild male factor infertility, anovulation, mild or minimal endometriosis, and unexplained infertility with at least one pate

• The miR signature of exosomes

  2019-05-09

  

  The miR signature of exosomes isolated from bulk prostate cancer buy ACY1215 (Fig. 1A, blue cells) and from their cancer stem cell compartment (Fig. 1A, green cells), display high levels of miR-21, miR-30 and miR-218 [23] (Fig. 1A, blue arrow). miR-21 and miR-30 have been identified as key regulato

• br The UN high level Summit for Refugees and Migrants

  2019-05-08

  

  The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p

• Based on the methodology used in previous studies

  2019-05-08

  

  Based on the methodology used in previous studies, the EGM source for the Wavelet algorithm has been nominally programmed as the Can-RV coil EGM [13]. As the nominal EGM source includes the generator, myopotentials induced due to body motion or other muscle activity are likely to influence the arrhy

• In this case report we described a rare

  2019-05-08

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• Cerrone et al reported that the mechanism of

  2019-05-08

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• Hay que remontar a la Guerra Civil espa

  2019-05-08

  

  Hay que remontar adrenergic antagonist la Guerra Civil española que movilizó a los poetas hispanoamericanos de una manera mucho más urgente que la Segunda Guerra Mundial, para hallar el origen de los lazos de Octavio Paz con Chile. En 1937 Octavio Paz recibió una invitación para participar en el Con

• The investigators suggest use of

  2019-05-08

  

  The investigators suggest use of doxycycline, which is effective for both diseases, as a possible empirical treatment at the primary level of care. Because the consequences of an untreated true case of rickettsiosis or leptospirosis are much greater than are those of unnecessary treatment, Mayxay an

• br Universalismo cosmopolitismo y pol

  2019-05-07

  

  Universalismo, cosmopolitismo y políticas culturales La conciencia universalista y el cosmopolitismo han sido productos de los movimientos y de los intercambios cada vez más acelerados de nuestro mundo. Desde las expansiones mercantiles y católicas del siglo xvi, los parámetros y los referentes a

• Chronic hepatitis B virus HBV infection is prevalent in many

  2019-05-07

  

  Chronic LY335979 virus (HBV) infection is prevalent in many Asian countries, notwithstanding three decades of universal hepatitis B vaccination programs. The invention of nucleos(t)ide analogs (NUCs) was a breakthrough in the treatment of chronic hepatitis B (CHB). However, HBV continues to be a ch

• THZ2 Regarding the pathophysiology of HF with preserved LVEF

  2019-05-07

  

  Regarding the pathophysiology of HF with preserved LVEF, AF is one of the most important precipitating factors related to diastolic dysfunction [22,23]. AF might have important roles in the pathogenesis of HF with preserved EF in association with diastolic HF. Compared with JCARE-CARD, which include

• br Discussion ELT is a

  2019-05-07

  

  Discussion ELT is a well-recognized complication of a dual chamber pacing system.[1,2] This is a wide QRS tachycardia resulting from the sensing of retrograde P-waves by the pacemaker, consequently triggering ventricular pacing beyond the programmed PVARP. Retrograde P-waves are induced by ectopi

• After exclusion of secondary causes of

  2019-05-07

  

  After exclusion of secondary causes of eosinophilia, diagnostic evaluation of primary eosinophilias relies on a combination of morphologic review of the blood and marrow, standard cytogenetics, fluorescent in situ hybridization, flow immunocytometry, and T-cell clonality assessment to detect histopa

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