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Introduction Cancer therapy has evolved throughout the decad
2019-04-28
Introduction Cancer therapy has evolved throughout the decades and is beginning to branch off into new and exciting fields including immunotherapy. The hope of this new field stems from the lack of success of chemotherapy in general. Chemotherapy\'s cytotoxic characteristics were regarded as one of
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Arita et al reported that the
2019-04-28
Arita et al. reported that the mechanism of ST-segment elevation in inferior leads is right coronary artery hypoperfusion due to vasodilation by Bezold–Jarisch-like reflexes that are induced by stimulation of the Senexin B in the intra-atrial septum during transseptal puncture and extension [3]. So
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Complete surgical resection of the tumor at the
2019-04-28
Complete surgical resection of the tumor at the time of diagnosis is essential towards effective management of PPB. Unfortunately, a large cohort of patients present with an advance stage of disease where the tumor has grown to such an extent to invade surrounding vital structures, hindering the com
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br Conclusions It is now
2019-04-28
Conclusions It is now clear that a number of chemokine receptor antagonist are involved in inherited bradyarrhythmia. Recent genetic studies have demonstrated that inherited arrhythmia is attributable to many genes with diverse functions. While the precise underlying mechanisms remain to be eluc
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El n mero de correspondiente
2019-04-28
El número 61 de , correspondiente al segundo semestre de 2015, ofrece seis artículos en su sección Política y Sociedad. El primero cgrp antagonist cargo de Wilfredo Padrón Iglesias, “La masonería, un punto sombrío en la trayectoria de Francisco de Miranda”, trata sobre esta importante figura, quien
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Grimson volver a a coordinar la quinta
2019-04-28
Grimson volvería (±)-Nutlin-3 coordinar la quinta reunión del grupo en Porto Alegre, en 2004. Sin embargo, no será él sino Mato quien, en 2005, reeditará 21 de los ensayos incluidos en las pasadas antologías en el libro Cultura, política y sociedad. Perspectivas latinoamericanas. La publicación pued
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Herweg et al evaluated the benefit of CRT in
2019-04-26
Herweg et al. [9] evaluated the benefit of CRT in 10 consecutive patients with NYHA class IV HF who were dependent on inotropic support. Their patients had received inotropic support for 146±258 days, and all patients were alive at the mean follow-up of 1088±284 days after CRT. They also reported an
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Therefore other imaging techniques and
2019-04-26
Therefore, other imaging techniques and tools have been evaluated. The results of this study add to the body of evidence demonstrating the value of SPECT and the need for a multifactorial approach to patient selection for CRT and in evaluating potential predictors of CRT response in non-ischemic pat
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Different ideas however emerged in the s and s in
2019-04-26
Different ideas, however, emerged in the 1960s and 1970s in the minds of computational biologists interested in the theory of wave propagation in excitable media. Based on chemical [17] and numerical experiments, [18] scientists in the Soviet Union and the USA began to suggest that fibrillation was
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Moore et al in a study of
2019-04-26
Moore et al., in a study of 40 patients with sarcoidosis and musculoskeletal symptoms, found intramedullary bone lesions on MRI in 43% of patients (17/40) [5]. The lesions ranged in size from 1 to 4cm. Lesions of the large bones and MLN 9708 manufacturer were present in 33% of patients (13/40), 9 of
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Aunque m s por afinidad electiva que por
2019-04-26
Aunque más por afinidad electiva que por propia decisión del autor, lo cierto es que justamente ese conjunto de rasgos aproximaría la obra al llamado libro de artista, modalidad creativa tan característicamente vanguardista como la simulación crítica, la interdisciplinariedad, el collage, el disposi
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The functional analysis of this V fsX
2019-04-26
The functional analysis of this V1764fsX1786 mutation is shown in Fig. 3B; no current was observed, indicating severe loss-of-function. Although we did not investigate the mechanisms of this complete reduction in Na+ current in this mutation, Herfst et al [19]. reported a similar frameshift mutation
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br Growth supportive characteristics of the
2019-04-25
Growth-supportive characteristics of the BM vascular niche Similar to normal tissues, tumours also need functional blood vessels to support their growth via the delivery of oxygen and nutrients. When a DTC starts proliferating into a micrometastasis, it drives angiogenesis to build new blood vess
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Regarding the expression of NKp NCR Fig A and B
2019-04-25
Regarding the expression of NKp46/NCR1 (Fig. 1A and B), both increased and decreased expression are observed depending on patients. Interestingly, the expression of the inducible molecule NKp44/NCR2 is clearly induced in 3 patients (PT1, PT2 and PT5) both regarding the percentage and the MFI. In con
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SQTS is relatively rare but should be considered if
2019-04-25
SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for
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