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The mesh has to be tailored in accordance with
2018-11-12
The mesh has to be tailored in accordance with the size and shape of the defect; fortunately, the malleability of the titanium material facilitates restoration of symmetric orbital socket conformation in three dimensions. It is still necessary to move the mesh plate in and out repetitively from the
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The prevalence and concentration of Giardia cysts in the
2018-11-12
The prevalence and concentration of Giardia cysts in the different locations are shown in Table 1. Sewage effluent samples showed the highest contamination with cysts (50.0%) followed by water from Nhue river (25.0%), canal water (21.7%), composted waste (20.0%), fishpond water (18.7%) and vegetable
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In a word nothing is interfacing with the
2018-11-12
In a word, nothing is interfacing with the mucosal linings of digestive tract more than food, which is proved to be a typical polydisperse system, containing micro- and nanoparticles. The uptake of these nanoparticles undoubtedly predominate all the mucosal nanoparticles uptake events. However, hard
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A study by Hu et al examined
2018-11-12
A study by Hu et al. [59] examined the effects of combined fucoxanthin and conjugated linoleic ionophore on high-fat diet-induced obesity in rats. The animals were fed a high-fat diet (control), supplemented with two doses of fucoxanthin or low-dose fucoxanthin plus conjugated linoleic acid for 52
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Both CAR and DAF have been
2018-11-12
Both CAR and DAF have been implicated in CVB infection. Molecular events underlying CVB entry have been described for polarized (Coyne and Bergelson, 2006) and nonpolarized gpr120 agonist (Patel et al., 2009). However, the exact mechanism involved in CVB infection of cardiomyocytes is unknown. More
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The immunophenotype of all three populations
2018-11-12
The immunophenotype of all three populations was comprehensively compared using a panel of 81 PE-conjugated TAPI-1 Supplier (Supplementary Table 1). A heat map showed extensive congruence in the percentage of cells positive for a given CD epitope between the three populations, although hierarchical
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Because many growth factors function in a context
2018-11-12
Because many growth factors function in a context-dependent manner, we explored the effects of adding WNT3A to the MC on the growth of Bl-CFCs. In cultures containing a combination of hematopoietic growth factors (VEGF, SCF, IL-3, IL-6, thrombopoietin [TPO], EPO, and FLT3L), 0.2%–0.6% of cyp450 indu
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In this study we have described methods
2018-11-12
In this study we have described methods for the selective isolation of primitive hMSCs that may prove advantageous both experimentally and therapeutically. The identification of the combination marker LTV makes it possible to prospectively isolate functional hMSCs directly from BM. Using these cells
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The model of this current study showed that CD
2018-11-12
The model of this current study showed that CD133 and CD24 markers, as a single or combined expression, are so promiscuous that they are not able to identify a pure population of adult renal stem cells. In PKHhigh cells, the only cell population presenting self-renew and an in vitro multipotency cap
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Oncolytic adenoviruses seem like ideal candidates to target
2018-11-12
Oncolytic adenoviruses seem like ideal candidates to target cancer initiating cells because they are cytotoxic and are not subject to the typical mechanisms of drug resistance, such as drug efflux pumps and defective apoptotic signaling. Indeed, studies with oncolytic adenoviruses in breast and 4 me
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The effects of TLQP on neurogenesis
2018-11-12
The effects of TLQP-62 on neurogenesis are thus similar to what is reported for antidepressant fluoxetine and serotonin (5-HT), both of which increase the proportion of undetermined Type 2a NPCs marked by Nestin+ and DCX-immunostaining and lacking the radial glial-like morphology (Boku et al., 2011;
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We show that the PB transposon and its
2018-11-12
We show that the PB transposon and its transposase are functional and quite efficient in terms of stable gene transfer to primary mesoangioblasts when compared to the transfection of plasmid vectors. Transposition occurred even when using large transposons comprising two expression cassettes and a s
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Finally we provide molecular evidence for PB transposase act
2018-11-12
Finally, we provide molecular evidence for PB transposase activity in vivo after plasmid intramuscular injection and electrotransfer of the murine muscles, for instance from the recovery and sequencing of several transposon–genomic junctions. Interestingly, such integration events were not able to m
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Recently several studies have suggested that peripheral bloo
2018-11-09
Recently, several studies have suggested that peripheral blood mononuclear protease inhibitors (PBMCs) are a promising resource for generating iPSCs because most of these cells do not undergo TCR rearrangement (Loh et al., 2010; Mack et al., 2011; Seki et al., 2010). However, PBMCs are composed of s
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Our findings directly interface with the role of CXCL SDF
2018-11-09
Our findings directly interface with the role of CXCL12 (SDF1)/CXCR4 signaling in adult HSPC migration: CXCL12 levels increase in response to stress and inflammation, and influence HSPC mobilization and extravasation within the adult BM (Dar et al., 2006). As hematopoietic niches are hypoxic during
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