• Oxysterols serve as endogenous ligands of liver X receptors

  2018-11-07

  

  Oxysterols serve as endogenous ligands of liver X receptors (LXRα (NR1H3)/LXRβ (NR1H2)) (Janowski et al., 1996). In addition to their established role in cholesterol metabolism (Janowski et al., 1999), LXRs also suppress inflammatory gene expression, thus controlling immune response and inflammation

• We have also observed that elevated

  2018-11-07

  

  We have also observed that elevated Glut1 on monocytes is associated with high sCD163 plasma levels within this HIV+ population, supporting a model by which chronic HIV infection drives metabolic activation of monocytes in response to inflammatory changes. This results from metabolic reprogramming w

• br Experimental design materials and methods

  2018-11-07

  

  Experimental design, materials and methods Material availability and repository The expression vectors described in this work are part of the SEVA initiative (http://wwwuser.cnb.csic.es/~seva/, [2,17]) and are available free of charge upon request. Acknowledgments Authors are indebted to S

• procyanidin b2 br Acknowledgments The CSGID project has

  2018-11-07

  

  Acknowledgments The CSGID project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contracts nos. HHSN272200700058C and HHSN272201200026C. We thank S

• ELA causes children to experience their environment

  2018-11-07

  

  ELA causes children to experience their environment as threatening, perceiving themselves as having no value and regarding the future as being not trustworthy (Dube et al., 2003). A history of ELA consequentially increases the risk of developing a psychiatric disorder in adulthood (Rojo-Moreno et al

• Structural neuroimaging studies have indicated

  2018-11-07

  

  Structural neuroimaging studies have indicated that volumes of several calpain inhibitor 1 areas are smaller in heavy adult MJ users especially in areas enriched with cannabinoid 1 (CB1) receptors, such as medial temporal lobe, and prefrontal cortex (Lorenzetti et al., 2010). Studies of adult chron

• br Method br Results br Discussion

  2018-11-07

  

  Method Results Discussion Our aim was to investigate whether differences in infants’ socioeconomic background were associated with resting EEG power at birth, and if those differences were correlated with later memory and language performance at 15 months of age. We found no correlations be

• br Conclusions br Conflict of interest br Acknowledgments Th

  2018-11-07

  

  Conclusions Conflict of interest Acknowledgments This work was supported by a Human Frontiers Science Program Young Investigator Grant nr. RGY 0073/2014, the LABEX EFL (ANR-10-LABX-0083>) and the ANR grant nr. ANR-15-CE37-0009-01 awarded to Judit Gervain. We thank the staff of the maternity

• br Discussion of the findings This study aimed

  2018-11-06

  

  Discussion of the findings This study aimed at determining the relationship between constraints management and capacity utilization of tea processing firms in Kenya. This study focused on the constraints management and further tested whether constraints management could lead to improved capacity

• The fact that ownership forms differ suggests that the way

  2018-11-06

  

  The fact that ownership forms differ suggests that the way the principals will organize their firms may differ based on the ownership structure. One pointer to this is that Chua et al. (2009) in their study of family firms found that the structure of family firms vary from that of non-family firms.

• Introduction Osteonecrosis of the femoral head

  2018-11-06

  

  Introduction Osteonecrosis of the femoral head (ONFH) is a pathologic condition of the hip joint that was previously referred to as avascular necrosis (AVN). Disruption of the blood supply to the femoral head is commonly believed to cause bone necrosis and further hip joint destruction. As early as

• Introduction Different responses among the sexes

  2018-11-06

  

  Introduction Different responses among the sexes are increasingly recognized as a major factor in the outcome of patients with trauma and sepsis. In the past years, several animal studies revealed that females had advantageous immunologic and cardiovascular responses during infectious challenges. I

• Current evidence indicates that the main

  2018-11-06

  

  Current evidence indicates that the main reservoirs of zoonotic Cryptosporidium remain livestock, with the potential transmission of C. parvum (= C. pestis (see Slapeta, 2011)), although other species, and genotypes, have been reported in humans but only occasionally (Slapeta, 2013). Susceptibility

• Oxidative stress status occurs when ROS accumulate Superoxid

  2018-11-06

  

  Oxidative stress status occurs when ROS accumulate. Superoxide dismutases (SOD), one of antioxidant enzymes, catalyzes the dismutation of superoxide anion () into O2 and hydrogen peroxide (H2O2). Subsequently, H2O2 is reduced to H2O by glutathione peroxidase (GSH-Px) in the cytosol, or by catalase (

• Our results also appear to be in line

  2018-11-06

  

  Our results also appear to be in line with earlier observations that ABCG2 expressing cells are overall smaller than cells positive for CK3 (de Paiva et al., 2006; Kim et al., 2004). As to the effect of oxygen, it is interesting to note that both the ABCG2+ and CK3+ were in general larger in sub-amb

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